Paired-Tag: Single-cell epigenetic profiling at high-throughput
Map out epigenome-transcriptome relationships at cell resolution
Paired-Tag revolutionizes single-cell analysis by enabling antibody-targeted profiling of histones or transcription factors, along with RNA. This platform facilitates precise annotation of cis-regulatory elements, linking their states directly to gene activity.
By identifying epigenetically-defined cell states, Paired-Tag provides crucial insights into cellular functions and disease mechanisms, enhancing the scope of genomic research.
A Vision of Compatibility
Your choice of platform is no barrier
Embrace unparalleled flexibility with Paired-Tag, designed to transcend platform limitations and integrate with any cell barcoding strategy. Whether your lab utilizes droplet-based systems, combinatorial barcoding, or emerging tagging technologies, Paired-Tag kits are crafted to ensure flawless compatibility.
This adaptability allows your team to leverage existing setups, eliminating the need for costly new equipment and enabling seamless adoption of state-of-the-art single-cell multi-omics, regardless of the chosen platform.
Decoding Disease Chromatin States
Using Paired-Tag for mechanistic insights
Dive deeper into the cellular narrative with Paired-Tag’s multiomic assay, which combines our sophisticated cellular histone state and epigenetic factor profiling with RNA-seq.
This powerful combination allows you to uncover disease-associated epigenetic states, linking them directly to gene expression patterns in development and disease.
By revealing how chromatin modifications influence RNA activity in across context and cells, Paired-Tag provides essential insights to drive forward the development of targeted therapies and diagnostic strategies.
