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Multiplex Droplet Paired-Tag Multi-Ome Kits

Product
Format
Catalogue
Multiplex Droplet Paired-Tag
4x4 rxns
EP2002
Multiplex Droplet Paired-Tag
4 rxns
EP2001

Multiplex Droplet Paired-Tag Kits extend the Droplet Paired-Tag Kits by adding additional molecular barcodes, enabling multiple antibody-treated samples to be multiplexed in the same single-cell lane, significantly lowering the per-cell cost of these assays, while maintaining the usability of DNA fragments – even from multiplet droplets.

A publication-quality image showing single-cell UMAP embeddings from multiple components of the Paired-Tag joint assay: RNA, H3K27ac, H3K27me3, H3K9me3, H3K4me1

Multiplex Droplet Paired-Tag is an advanced assay designed to harness the power of single-cell epigenetic and transcriptomic profiling while maximizing efficiency and scalability. With the proliferation of single-cell studies, there is a growing demand for techniques that offer not only precision but also cost-effectiveness, and Multiplex Droplet Paired-Tag fits this niche perfectly.

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Building upon the foundational Droplet Paired-Tag technology, the Multiplex version introduces extended tagmentation barcodes. This novel feature permits the labeling of antibodies and samples in a manner that cells from multiple samples can be conveniently pooled and processed in the same cell barcoding lane. This multiplexing capability considerably reduces the per-cell cost of the assays, making large-scale studies more economically feasible.

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Furthermore, despite the pooling of cells from various samples, the Multiplex Droplet Paired-Tag Kit ensures the integrity and usability of DNA fragments. Even in the case of multiplet droplets, the extracted data remains uncompromised, allowing for accurate and reliable downstream analyses.

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The Multiplex Droplet Paired-Tag Kit offers researchers a seamless balance between complexity and efficiency, pushing the boundaries of what's achievable in single-cell studies.

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